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  "Package": "denovolyzeR",
  "Title": "Statistical Analyses of De Novo Genetic Variants",
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  "Description": "An integrated toolset for the analysis of de novo\n(sporadic) genetic sequence variants. denovolyzeR implements a\nmutational model that estimates the probability of a de novo\ngenetic variant arising in each human gene, from which one can\ninfer the expected number of de novo variants in a given\npopulation size. Observed variant frequencies can then be\ncompared against expectation in a Poisson framework.\ndenovolyzeR provides a suite of functions to implement these\nanalyses for the interpretation of de novo variation in human\ndisease.",
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  "Date/Publication": "2016-08-30 19:57:27 UTC",
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      "page": "denovolyze",
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        "denovolyzeByClass",
        "denovolyzeByGene"
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      "title": "A package for the analysis of _de novo_ sequencing variants",
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