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  "Package": "denovolyzeR",
  "Title": "Statistical Analyses of De Novo Genetic Variants",
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  "Date": "2016-08-01",
  "Authors@R": "c(\nperson(\"James\",\"Ware\",email=\"j.ware@imperial.ac.uk\",role=c(\"aut\",\"cre\")),\nperson(\"Jason\",\"Homsy\",role=\"ctb\"),\nperson(\"Kaitlin\",\"Samocha\",role=\"ctb\")\n)",
  "Description": "An integrated toolset for the analysis of de novo\n(sporadic) genetic sequence variants. denovolyzeR implements a\nmutational model that estimates the probability of a de novo\ngenetic variant arising in each human gene, from which one can\ninfer the expected number of de novo variants in a given\npopulation size. Observed variant frequencies can then be\ncompared against expectation in a Poisson framework.\ndenovolyzeR provides a suite of functions to implement these\nanalyses for the interpretation of de novo variation in human\ndisease.",
  "License": "GPL-3",
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  "URL": "http://denovolyzeR.org",
  "BugReports": "http://github.com/jamesware/denovolyzeR/issues",
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  "Repository": "https://jamesware.r-universe.dev",
  "Date/Publication": "2016-08-30 19:57:27 UTC",
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    "User": "root"
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    {
      "page": "denovolyze",
      "title": "Evaluates burden of _de novo_ variation against expectation",
      "topics": [
        "denovolyze",
        "denovolyzeByClass",
        "denovolyzeByGene"
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      "topics": [
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    {
      "page": "denovolyzeR",
      "title": "A package for the analysis of _de novo_ sequencing variants",
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        "denovolyzeR-package",
        "denovolyzeR"
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