Package: denovolyzeR
Title: Statistical Analyses of De Novo Genetic Variants
Version: 0.2.0
Date: 2016-08-01
Authors@R: c(
    person("James","Ware",email="j.ware@imperial.ac.uk",role=c("aut","cre")),
    person("Jason","Homsy",role="ctb"),
    person("Kaitlin","Samocha",role="ctb")
    )
Description: An integrated toolset for the analysis of de novo
        (sporadic) genetic sequence variants. denovolyzeR implements a
        mutational model that estimates the probability of a de novo
        genetic variant arising in each human gene, from which one can
        infer the expected number of de novo variants in a given
        population size. Observed variant frequencies can then be
        compared against expectation in a Poisson framework.
        denovolyzeR provides a suite of functions to implement these
        analyses for the interpretation of de novo variation in human
        disease.
Depends: R (>= 3.1.0)
Imports: dplyr (>= 0.3), reshape2 (>= 1.4)
License: GPL-3
LazyData: true
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
URL: http://denovolyzeR.org
BugReports: http://github.com/jamesware/denovolyzeR/issues
RoxygenNote: 5.0.1
Config/pak/sysreqs: libicu-dev
Repository: https://jamesware.r-universe.dev
Date/Publication: 2016-08-30 19:57:27 UTC
RemoteUrl: https://github.com/jamesware/denovolyzer
RemoteRef: HEAD
RemoteSha: badc99f8d69e81742b94c409f072448f0f2fcfae
NeedsCompilation: no
Packaged: 2026-10-08 13:04:22 UTC; root
Author: James Ware [aut, cre],
  Jason Homsy [ctb],
  Kaitlin Samocha [ctb]
Maintainer: James Ware <j.ware@imperial.ac.uk>